Abstract: This paper is to provide theoretical basis and research way for predictive control of the complex network control system. In this paper, the issue of the control for uncertain cyber–physical systems is developed. Considered the systems suffer from the actuator attack, a super-twisting control method is designed to defense the attack. Firstly, an integral sliding-mode function is presented, and the sliding-mode dynamics is analyzed. Then, the slide-mode parameter is solved by linear matrix inequality theory, and a super-twisting controller is synthesized based on the solved slide-mode parameter. Simutaneously, the finite-time convergence of the close-loop system is proved. Finally, an example is executed to verify the correctness of the proposed method.