Abstract: Accelerating the development of pilot-scale industrialization and constructing a modern pilot-scale industrial system are crucial for speeding up the transformation and application of China's scientific and technological achievements. This will foster a deeper integration between the innovation and industrial chains, propelling the industrialization of high-level scientific and technological achievements. Pilot-scale production in China holds both the potential and necessity for industrialization. Its effective operation hinges on robust internal management mechanisms, effective external collaboration, and efficient government macro-control measures. Currently, the industrialization of pilot-scale production in China faces several challenges, including inadequate communication between innovators and producers, risks of intellectual property breaches and talent attrition, low motivation among innovators, vague market positioning, and an incomplete regulatory framework. To address these issues, it is essential to continuously refine and enhance mechanisms for information flow, technical service protection, talent evaluation and recruitment, profit distribution, market specialization, and regulatory reforms.