(R)-3, 3'-二羧酸-1, 1'-联萘酚的合成

The Synthesis of (R)-3, 3′-dicarboxylic acid-1, 1′-binaphthylol

摘要: 手性联萘酚及其衍生物是一类重要的有机化合物, 广泛应用于不对称合成中。本文以手性联萘酚为原料, 三步合成了(R)-3, 3'-二羧酸-1, 1'-联萘酚, 三步总收率达到了68%。最后用红外、紫外和元素分析对中间体和最终产物的结构进行了表征。

Abstract: Chiral binaphthol and its derivatives are important organic compounds, which are widely used in asymmitric synthesis.In this paper(R)-3, 3′-dicarboxylic acid-1, 1′-binaphthylol was obtained from chiral binaphthol through three steps.The total yield was 68%.The structures of the derivatives are characterized by the infrared spectrum, ultra-violet spectrum and elemental analysis.